The paper "Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma", by Askar Obulkasim, ..., Mark van de Wiel, Heike Grabsch, is published in Oncotarget, June 2016. It uses the entropy notion developed by Wessel van Wieringen to demonstrate a reduction in genomic tumor heterogeneity among esophageal tumors due to neoadjuvant chemotherapy.